Previous studies have claimed that around 80% of autism risk will be present in genes inherited from parents.

Regardless that it was earlier believed that autism risk was solely linked to maternal genetic aspects, a recent study, which aimed to focus on the influence of each parents, found that siblings diagnosed with the condition had the next likelihood of inheriting the genes from their father slightly than their mother.

The findings of the research were published in Cell Genomics.

Scientists from Recent York’s Cold Spring Harbor Laboratory have been running a two-decade-long research on the genes related to autism. They’ve identified 1000’s of genes, which–if damaged or not working properly–could potentially play a task in a toddler being born with an autism spectrum disorder.

To achieve further insights, they conducted a radical evaluation of the genomes of over 6,000 families, who volunteered to take part in the study. By examining the genetic makeup of those families, they found when two or more children were diagnosed with autism, they were more genetically much like their father, in accordance with Health Day.

Nonetheless, it was yet not comprehended how the daddy’s genome had this impact.

“There are kids diagnosed with autism who’re high functioning,” said Ivan Iossifov, an associate professor at Cold Spring Harbor Laboratory and senior writer of the study, in a media release. “They’ve a very productive life, although they’ve some minor troubles in social interactions, as most of us do. But additionally, there are kids diagnosed with autism who never learn to talk, and so they have definitely a difficult life.”

One possible hypothesis is that certain fathers may carry genetic mutations which have a protective effect against autism. Nonetheless, these protective mutations will not be transmitted to their children.

Alternatively, it’s also possible that fathers could pass on mutations that cause the mother’s immune system to mistakenly goal and attack the developing embryo. Nonetheless, this concept does suggest that the immune system’s reactions within the mother’s body may play a task in the event of autism in some cases.

This finding not only uncovers a further factor contributing to autism cases, but in addition raises one other query: could other health conditions follow similar genetic patterns?

“Our future research is exciting,” Iossifov said within the news release. “If one among those theories or two of them prove to be true, then it opens different treatment strategies, which may, in the longer term, affect quite numerous families.”

A latest study has found that common ear, nose, and throat (ENT) problems and upper respiratory infections in young children may indicate the next risk of autism.
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Published by Medicaldaily.com