Researchers have found that personalized medication for blood pressure treatment is more efficient in protecting people against future cardiovascular diseases.
A change of medication might be twice as great because the effect of doubling the dose of the patient’s current medication, a recent study revealed.
Hypertension has grow to be one of the crucial prevalent health conditions within the U.S., affecting greater than 116 million people. Most individuals with hypertension need lifestyle modifications corresponding to exercise, food regimen control, and cutting down on alcohol consumption and smoking. Nevertheless, along with these behavioral changes, doctors may prescribe medications for some people to bring blood pressure under control.
There are several forms of blood pressure medicines corresponding to diuretics, beta-blockers, and ACE inhibitors. The doctors determine the variety of medication based on the underlying reason behind an individual’s hypertension and other health conditions.
Researchers from Uppsala University in Sweden conducted a recent study to know the efficiency of various blood pressure-lowering medications on 280 individuals over a 12 months, the Hindustan Times reported.
Earlier research indicated that only a fifth of people that used drug therapy within the country could bring blood pressure under control.
The scientists hypothesized that the reduced efficiency was because each blood pressure drug had a distinct effect on each individual. Since there are a whole lot of drugs available, a patient may not receive the optimal drug at the primary attempt, which could reduce the efficiency of the drug therapy and cause unnecessary unwanted side effects.
The study tested 4 different blood pressure medicines–Lisinopril (angiotensin-converting enzyme inhibitor), Candesartan (angiotensin-receptor blocker), Hydrochlorothiazide (thiazide), and Amlodipine (calcium channel blocker).
The researchers found the efficiency of the drug varied widely from individual to individual. Additionally they found that certain patients achieved lower blood pressure from one drug than from one other.
“The effect of a change of medication might be twice as great because the effect of doubling the dose of the patient’s current medication. It was clear in our study that certain patients achieved lower blood pressure from one drug than from one other. This effect is large enough to be clinically relevant,” Johan Sundstrom, cardiologist and Professor of Epidemiology at Uppsala University and the primary writer of the study, said.
The findings of the study published within the Journal of the American Medical Association challenge the present strategy of hypertension drug therapy that recommends medicines from the 4 drug groups equally for all patients with hypertension.
“If we personalize each patient’s medication, we will achieve a greater effect than if we elect a drug from one in every of these 4 drug groups at random. Given the precise blood pressure drug, [patients] can probably obtain higher protection against future cardiovascular diseases more quickly,” Sundström added.
The researchers found that the efficiency of the blood pressure drug varied widely from individual to individual.
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