For all those frustrated with pimples treatments, here is a few excellent news. Scientists say a latest game-changing technique to clear those breakouts is within the works.
In accordance with the most recent study, published within the journal Nanoscale, nanoparticle delivery of narasin, an antibiotic compound, could work effectively against drug-resistant bacteria that cause Pimples vulgaris.
Pimples vulgaris is a chronic inflammatory disorder that causes bumps and skin lesions on the face, upper arms, trunk and back. The skin condition often gets triggered during adolescence by the bacteria Cutibacterium acnes.
Certain aspects equivalent to stress, air pollution, medication and the usage of oily skincare products can worsen breakouts. The condition affects around 80% of individuals between the ages of 11 to 30.
The treatment typically involves the usage of topical pimples medications that contain retinoids, salicylic acid and antibiotics. Using antibiotics often helps to curb bacterial growth, but lots of them turn out to be ineffective because the bacteria adapt.
“To enhance the clinical management of this disease, there may be a pressing clinical demand to develop revolutionary antibacterial therapies that utilize novel mechanisms. The present research aimed to find the antibacterial efficacy of narasin (NAR), a polyether ionophore, against drug-resistant pimples bacteria,” the researchers wrote.
The proposed treatment involves the usage of narasin because it has not yet developed drug resistance. Narasin is an antibacterial compound used to treat infections in livestock and poultry.
Researchers found that nanoparticle delivery of the compound could significantly boost the treatment as it could penetrate much deeper into the skin where the bacteria thrive. A treatment gel developed by them stayed stable at room temperature for 4 weeks.
The team found the treatment effective against Cutibacterium acnes when tested under laboratory conditions. They plan to check it on humans.
“Pimples severely impacts roughly 9.4 percent of the world’s population, mainly adolescents, and causes distress, embarrassment, anxiety, low self-confidence and social isolation amongst victims,” study creator Fatima Abid said. “Although there are a lot of oral medications prescribed for pimples, they’ve a spread of detrimental uncomfortable side effects, and plenty of are poorly water-soluble, which is why most patients and clinicians prefer topical treatments.”
Published by Medicaldaily.com